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NPA1 Polyclonal Antibody, 50ul Organelle Studies The encoded protein is a

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NPA1 Polyclonal Antibody, 50ul Organelle Studies The encoded protein is aURB1, also named as C21orf108, KIAA0539 and NPA1, is a 2271 amino acid protein that is homologous to the S. cerevisiae protein URB1 which is a nucleolar protein involved in the normal accumulation of 25S and 5. S rRNAs and may also play a role in the biosynthesis of the 60S ribosomal unit. Also localized to the nucleolus, human URB1 is thought to have the same functions as S. cerevisiae URB1. The antibody is specific to URB1.

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Description

The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells

The encoded membrane-bound protein localizes to the cell surface

A protein encoded by the upstream ORF was found in skeletal muscle| whereas the encoded protein from the downstream ORF was found only in testis

The osteoglycin induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation

a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal

NPA1 Polyclonal Antibody, 50ul Organelle Studies The encoded protein is aURB1, also named as C21orf108, KIAA0539 and NPA1, is a 2271 amino acid protein that is homologous to the S. cerevisiae protein URB1 which is a nucleolar protein involved in the normal accumulation of 25S and 5. S rRNAs and may also play a role in the biosynthesis of the 60S ribosomal unit. Also localized to the nucleolus, human URB1 is thought to have the same functions as S. cerevisiae URB1. The antibody is specific to URB1.

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