RNase III Drosha Polyclonal Antibody, 100ul Centrifugal Filter FUNDC1 encodes a protein with

FUNDC1 encodes a protein with a FUN14 superfamily domain

and two MAGE domains in the C-terminus

This protein is a ligand for TNFRSF14

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

PKC family members also serve as major receptors for phorbol esters

RNase III Drosha Polyclonal Antibody, 100ul Centrifugal Filter FUNDC1 encodes a protein withMembers of the ribonuclease III superfamily of double stranded (ds) RNA specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al. 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al. 2003 [PubMed 14508493]).