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IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers SMARCB1 has been found to

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IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers SMARCB1 has been found toThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

SMARCB1 has been found to be a tumor suppressor

This gene encodes a member of the family of secreted protein kinases

The encoded protein can multimerize and may function as an ion channel

which has many cysteine residues with conserved spacing

Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4

IκB-alpha Polyclonal Antibody, 50ul[BT-AP10545] Gel & Buffers SMARCB1 has been found toThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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