FBXL4 Rabbit Polyclonal Antibody, 20ul Centrifuges Its protein inhibits activated C1r

Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation

serves as a receptor for the inflammatory peptide C5a

Also expressed in certain liver and kidney carcinomas

the alpha-A and alpha-B subunits have a 3:1 ratio

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired

FBXL4 Rabbit Polyclonal Antibody, 20ul Centrifuges Its protein inhibits activated C1rThis gene encodes a member of the F box protein family which are characterized by an approximately 40 amino acid motif the F box. F box proteins constitute one subunit of modular E3 ubiquitin ligase complexes called SCF complexes which function in phosphorylation dependent ubiquitination. The F box domain mediates protein protein interactions and binds directly to S phase kinase associated protein 1. In addition to an F box domain the encoded protein