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p57(Phospho Thr310) Polyclonal Antibody, 20ul Roller Bottles An important paralog of this

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p57(Phospho Thr310) Polyclonal Antibody, 20ul Roller Bottles An important paralog of thisThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

An important paralog of this gene is NDUFC2-KCTD14

It has been shown to mediate the immunosuppressive signal of interleukin 10

Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways

Peroxiredoxin 3 is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase

Neural retina leucine zipper is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function

p57(Phospho Thr310) Polyclonal Antibody, 20ul Roller Bottles An important paralog of thisThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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