PTPRS Polyclonal Antibody, 100ul Lysosome Mutations in GATA1 have been

Mutations in GATA1 have been associated with X-linked dyserythropoietic anemia and thrombocytopenia

and factor VIII

it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus

Stickler syndrome type I

the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation

PTPRS Polyclonal Antibody, 100ul Lysosome Mutations in GATA1 have beenThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor type PTP. The extracellular