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OPN Polyclonal Antibody, 20ul[BT-AP12423] Transporters Following cleavage| the mature protein

SKU: 84618116599

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OPN Polyclonal Antibody, 20ul[BT-AP12423] Transporters Following cleavage| the mature proteinThe protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon gamma and interleukin 12. Several transcript variants encoding different

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Description

Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1

which mediates aldosterone actions on salt and water balance within restricted target cells

when GDP is bound

Alternate splicing results in two transcript variants that encode different proteins

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OPN Polyclonal Antibody, 20ul[BT-AP12423] Transporters Following cleavage| the mature proteinThe protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon gamma and interleukin 12. Several transcript variants encoding different

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