ARHGEF10 Polyclonal Antibody, 100ul Inoculating Loops/Needles but causes G2-M arrest in

but causes G2-M arrest in p53-null or –mutant cells

or activity

GO annotations related to this gene include receptor binding and GABA receptor binding

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

CNPase acts as a microtubule-associated protein by promoting microtubule assembly

ARHGEF10 Polyclonal Antibody, 100ul Inoculating Loops/Needles but causes G2-M arrest inARHGEF10 encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in ARHGEF10 are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants.