HDAC5(Phospho Ser498) Polyclonal Antibody, 20ul Organelle Studies Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1

Catalytic activity:NADH + ubiquinone = NAD(+) + ubiquinol

May exert a regulatory function in meiotic events that are required for terminal differentiation of male germ cell

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

The encoded protein can also stimulate adenovirus replication in vitro

HDAC5(Phospho Ser498) Polyclonal Antibody, 20ul Organelle Studies Alternative splicing results in multipleHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3