p53(Phospho Ser9) Polyclonal Antibody, 100ul Reservoirs Studies of the mouse and

Studies of the mouse and chick homologs revealed roles in midbrain and limb development

Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4)

The product of this gene is an enzyme involved in lipid metabolism| and it encodes cytosolic acetoacetyl-CoA thiolase

the protein has a distinct punctate nucleolar localization

The full length form is the transmembrane protein

p53(Phospho Ser9) Polyclonal Antibody, 100ul Reservoirs Studies of the mouse andThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.