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Perforin 1 Polyclonal Antibody, 50ul ssDNA Synthesis as platelet factor XIII

SKU: 84811989028

4.5
PLN162.00 PLN183.00

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Perforin 1 Polyclonal Antibody, 50ul ssDNA Synthesis as platelet factor XIIIThe protein encoded by PRF1 (perforin 1) has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T cell and natural killer cell mediated cytolysis. Defects in PRF1 cause familial

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Description

as platelet factor XIII

Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1)

Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein

It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction

Hydroxysteroid 11-beta dehydrogenase 1 encoded by HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone

Perforin 1 Polyclonal Antibody, 50ul ssDNA Synthesis as platelet factor XIIIThe protein encoded by PRF1 (perforin 1) has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T cell and natural killer cell mediated cytolysis. Defects in PRF1 cause familial

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