RBPJL Polyclonal Antibody, 100ul Antibodies Mutations in ITCH are a

Mutations in ITCH are a cause of syndromic multisystem autoimmune disease

is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure

SRF encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation

It has Catalytic activity for class I and II ArfGAPs in vitro

Alternative splicing results in multiple transcript variants

RBPJL Polyclonal Antibody, 100ul Antibodies Mutations in ITCH are aThis gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein Barr virus nuclear antigen 2. Alternative splicing results in multiple transcript variants.