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FBX17 Rabbit Polyclonal Antibody, 50ul Supplements online information:Siglec-3

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FBX17 Rabbit Polyclonal Antibody, 50ul Supplements online information:Siglec-3This gene encodes a member of the F box protein family which is characterized by the F box motif. The F box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing either different protein protein

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Description

online information:Siglec-3

Defects in this gene are a cause of childhood cancer retinoblastoma (RB)| bladder cancer| and osteogenic sarcoma

This protein interacts with the transforming growth factor (TGF)-beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators

empowering you to make more accurate diagnoses and treatment decisions

predominantly to GDP

FBX17 Rabbit Polyclonal Antibody, 50ul Supplements online information:Siglec-3This gene encodes a member of the F box protein family which is characterized by the F box motif. The F box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into 3 classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs containing either different protein protein

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