GP161 Polyclonal Antibody, 20ul Sealing Film Pseudogenes of this gene are

Pseudogenes of this gene are found on chromosomes 1

Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome

Can form homomultimers and heteromultimers with GRIP1 (By similarity)

Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene

HLA-DMB belongs to the HLA class II beta chain paralogues

GP161 Polyclonal Antibody, 20ul Sealing Film Pseudogenes of this gene areUpon ligand binding, G protein coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008