SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture This gene encodes a member

This gene encodes a member of the histidine triad (HIT) superfamily

Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes

The active form of the protein is found extracellularly as a homodimer

Mutations in this gene cause autosomal dominant severe congenital neutropenia

This gene belongs to the chemokine-like factor gene superfamily

SPAK(Phospho Ser323) Polyclonal Antibody, 50ul 3D Culture This gene encodes a memberThis gene encodes a serine threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation chloride coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the