FKB1A Polyclonal Antibody, 100ul Immunology subcellular location:Distributed throughout the cytoplasm

subcellular location:Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells

A mutation in this gene was found in a family with Stickler syndrome

This gene shares its 5' exon with the overlapping gene

The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex

The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth| development and metastasis

FKB1A Polyclonal Antibody, 100ul Immunology subcellular location:Distributed throughout the cytoplasmThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF beta receptor. It also interacts with multiple intracellular calcium