PI 3-Kinase p110Delta Polyclonal Antibody, 50ul Endonucleases & Exonucleases 11) chromosomal translocation involving this

11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia

STK10 encodes a member of the Ste20 family of serine/threonine protein kinases

as indicated for members 1-3

It activates the urokinase-type plasminogen activator

RB3 (Stathmin-4)

PI 3-Kinase p110Delta Polyclonal Antibody, 50ul Endonucleases & Exonucleases 11) chromosomal translocation involving thisPhosphoinositide 3 kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110 alpha p110 beta, and p110 gamma), the encoded protein binds p85 adapter proteins and GTP bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.