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PDE6G(Phospho Thr22) Rabbit Polyclonal Antibody, 50ul miRNA / siRNA Synthesis |pharmaceutical:A constitutively active FOXO4 mutant

SKU: 85671222652

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PDE6G(Phospho Thr22) Rabbit Polyclonal Antibody, 50ul miRNA / siRNA Synthesis |pharmaceutical:A constitutively active FOXO4 mutantThis gene encodes the gamma subunit of cyclic GMP phosphodiesterase which is composed of alpha and beta catalytic subunits and two identical inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues and has been shown to regulate the c Src protein kinase and G protein coupled receptor kinase 2. Alternative splicing results in

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Description

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12

It may also be related to the P2Y receptors

The piggyBac family of proteins

such as Gilson

PDE6G(Phospho Thr22) Rabbit Polyclonal Antibody, 50ul miRNA / siRNA Synthesis |pharmaceutical:A constitutively active FOXO4 mutantThis gene encodes the gamma subunit of cyclic GMP phosphodiesterase which is composed of alpha and beta catalytic subunits and two identical inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues and has been shown to regulate the c Src protein kinase and G protein coupled receptor kinase 2. Alternative splicing results in

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