DHE3 Rabbit Polyclonal Antibody, 50ul Immune Cell Analysis Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for GRM4

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

Interacts with MAFB

The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene

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DHE3 Rabbit Polyclonal Antibody, 50ul Immune Cell Analysis Several transcript variants encoding differentThis gene encodes glutamate dehydrogenase which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in