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Tau(Phospho Ser422) Polyclonal Antibody, 100ul Protein Research and its product is proposed

SKU: 85820899640

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Tau(Phospho Ser422) Polyclonal Antibody, 100ul Protein Research and its product is proposedThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,

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Description

and its product is proposed to play a role in human cellular senescence and tumor suppression

and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27

the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain

The protein encoded by this gene is part of a large multisubunit complex required for microtubule nucleation at the centrosome

This protein may also be involved in macrophage and granulocyte maturation

Tau(Phospho Ser422) Polyclonal Antibody, 100ul Protein Research and its product is proposedThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,

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