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STK36 Polyclonal Antibody, 100ul Cell Labeling & Imaging The protein encoded by this

SKU: 85836222266

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STK36 Polyclonal Antibody, 100ul Cell Labeling & Imaging The protein encoded by thisSTK36 encodes a member of the serine threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia.

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Description

The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family

The gene encoding RPS6KL1 maps to human chromosome 14

Protein inhibitor of activated STAT 1 plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TCF3

It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins

STK36 Polyclonal Antibody, 100ul Cell Labeling & Imaging The protein encoded by thisSTK36 encodes a member of the serine threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia.

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