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Cyclophilin B Monoclonal Antibody(1B3), 20ul Contamination Detection & Removal preferentially expressed in the nervous

SKU: 85840653981

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Cyclophilin B Monoclonal Antibody(1B3), 20ul Contamination Detection & Removal preferentially expressed in the nervousThe protein encoded by this gene is a cyclosporine binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T and B lymphocytes, and may regulate cyclosporine A mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

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Description

preferentially expressed in the nervous system

PubMed: 19218236

but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor

and spleen

Defects in this gene are a cause of pancreatic agenesis

Cyclophilin B Monoclonal Antibody(1B3), 20ul Contamination Detection & Removal preferentially expressed in the nervousThe protein encoded by this gene is a cyclosporine binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T and B lymphocytes, and may regulate cyclosporine A mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

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