P3H2 Polyclonal Antibody, 100ul Reagent Reservoirs AFF1 encodes a member of
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P3H2 Polyclonal Antibody, 100ul Reagent Reservoirs AFF1 encodes a member ofThis gene encodes a member of the prolyl 3 hydroxylase subfamily of 2 oxo glutarate dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross linking by catalyzing post translational 3 hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer.
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