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PS-1 Polyclonal Antibody, 100ul Protein Post-translational Modification Enjoy improved stability and versatility

SKU: 85867429289

4.2
PLN141.00 PLN180.00

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PS-1 Polyclonal Antibody, 100ul Protein Post-translational Modification Enjoy improved stability and versatilityAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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Description

Enjoy improved stability and versatility in your mixing tasks

mutations within this protein have been associated with ageing and bone loss

MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain

The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene

PS-1 Polyclonal Antibody, 100ul Protein Post-translational Modification Enjoy improved stability and versatilityAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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