p47-phox Polyclonal Antibody, 100ul[BT-AP06793] Endonucleases & Exonucleases This gene may be aberrently

This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas

Multiple transcript variants encoding different isoforms have been found for HRH4

These chains associate via disulfide linkages to form the heterodimeric enzyme

Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters

Defects in CYB5A are a cause of type IV hereditary methemoglobinemia

p47-phox Polyclonal Antibody, 100ul[BT-AP06793] Endonucleases & Exonucleases This gene may be aberrentlyThe protein encoded by NCF1 (neutrophil cytosolic factor 1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in NCF1 have been associated with chronic granulomatous disease.