Mcl-1 Polyclonal Antibody, 100ul[BT-AP05274] Gene Synthesis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been identified in this gene

This gene encodes the fatty acid binding protein found in liver

In the brain this peptide may be responsible for the effects of stress on appetite

Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity

In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

Mcl-1 Polyclonal Antibody, 100ul[BT-AP05274] Gene Synthesis Alternatively spliced transcript variants encodingMCL1 encodes an anti apoptotic protein, which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.