Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation In mice| expression of this

In mice| expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis

This gene encodes the second human homologue of the bacterial RuvB gene

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Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns

Binds to the consensus sequence 5'-

Phospho-5-LO (S272) Polyclonal Antibody, 100ul Cryopreservation In mice| expression of thisALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes