PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Mapped to a previously identified

Mapped to a previously identified cluster of cadherin genes on chromosome 16q22

including regulation of iron homeostasis

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT)

Overexpression of PMEPA1 may play a role in multiple types of cancer

The protein (BMX non-receptor tyrosine kinase) contains a PH-like domain

PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection Mapped to a previously identifiedPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.