P38 mouse Monoclonal Antibody(8C11), 50ul Cell fragmentation and collection Two regions of potential trinucleotide

Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein

Alternatively spliced transcript variants have been found

It has been suggested to be involved in several basic biological events such as cell death

and control of the activation of aspartic proteinase zymogens

Allelic variations in this gene are associated with heparin cofactor II deficiency

P38 mouse Monoclonal Antibody(8C11), 50ul Cell fragmentation and collection Two regions of potential trinucleotideThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its