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Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification PubMed: 25173806)

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Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification PubMed: 25173806)Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (By similarity). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (By similarity). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (By similarity). In addition, functions as wound related growth factor that acts

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PubMed: 25173806)

thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery

including Hirschsprung disease and some cancers

The majority of autoantibodies to p70 in most sera from patients with SLE seem to be reactive with this region

The amino acid sequence of this isozyme is 92% identical to that of rat homolog

Rat Progranulin, PGRN ELISA Kit, 96T Nucleic Acid Isolation & Purification PubMed: 25173806)Secreted protein that acts as a key regulator of lysosomal function and as a growth factor involved in inflammation, wound healing and cell proliferation (By similarity). Regulates protein trafficking to lysosomes and, also the activity of lysosomal enzymes (By similarity). Facilitates also the acidification of lysosomes, causing degradation of mature CTSD by CTSB (By similarity). In addition, functions as wound related growth factor that acts

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