Rat Telomere Repeat Binding Factor 2, TRF2 ELISA Kit, 96T Immunology Plays a role as tumor

Plays a role as tumor suppressor (By similarity)

[Isoform 1]: Acts as a weak transcriptional factor

Contains 1 RHD (Rel-like) domain

The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration

Contains 1 FCP1 homology domain

Rat Telomere Repeat Binding Factor 2, TRF2 ELISA Kit, 96T Immunology Plays a role as tumorMay modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro). Involved in starvation induced autophagy probably by its association with PI3K complex I (PI3KC3 C1). However, effects has been described variably. Involved in the induction of starvation induced autophagy. Stabilzes PI3KC3 C1 assembly and enhances ATG14 linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and