NEUR3 Rabbit Polyclonal Antibody, 20ul Immune Cell Preparation Mutations in this gene have

Mutations in this gene have been associated with familial dysautonomia

being cytoplasmic in the G2/M phase and accumulating in nucleus during the G1 phase

The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II

the small GTPase Rho

Myc Tag also can be used to isolate protein complexes with multiple subunits

NEUR3 Rabbit Polyclonal Antibody, 20ul Immune Cell Preparation Mutations in this gene haveThis gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.