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ERR2 Polyclonal Antibody, 50ul Palm Micro Centrifuges Mutations in GNAL have been

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ERR2 Polyclonal Antibody, 50ul Palm Micro Centrifuges Mutations in GNAL have beenThis gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development.

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Description

Mutations in GNAL have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia

This gene is involved in the regulation of uterine development and is required for female fertility

Higher levels of expression of this gene in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed

The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains

Constitutive activation of this gene caused either by somatic mutations| or genomic duplications of regions that include this gene| have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome

ERR2 Polyclonal Antibody, 50ul Palm Micro Centrifuges Mutations in GNAL have beenThis gene encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development.

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