TRAP240 Polyclonal Antibody, 100ul[BT-AP09183] Sealing Film Mutations in this gene are

Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia

It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors

Dematin actin binding protein encoded by DMTN is an actin binding and bundling protein that plays a structural role in erythrocytes

which is characterized by a distinctive mid-hindbrain and cerebellar malformation

Among its related pathways are Metabolism and Alanine

TRAP240 Polyclonal Antibody, 100ul[BT-AP09183] Sealing Film Mutations in this gene areMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.