Rat Peroxiredoxin 2, PRDX2 ELISA Kit, 96T Antibodies RAN is an androgen receptor

RAN is an androgen receptor (AR) coactivator that binds differentially with different lengths of polyglutamine within the androgen receptor

PubMed: 23629626)

This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein

neuronal migration

The encoded protein is also part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs

Rat Peroxiredoxin 2, PRDX2 ELISA Kit, 96T Antibodies RAN is an androgen receptorThiol specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor alpha by regulating the intracellular concentrations of H(2)O(2).