EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos Decreased expression of this gene

Decreased expression of this gene is associated with splenic marginal zone lymphomas

USP36 (ubiquitin specific peptidase 36) encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases

IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells

The encoded protein may be involved in endosome-to-Golgi transport

The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine

EI2BE Polyclonal Antibody, 50ul Custom DNA Oligos Decreased expression of this geneThis gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.