RSPO4 Rabbit Polyclonal Antibody, 50ul Centrifuges TPO-R deficient mice were severely

TPO-R deficient mice were severely thrombocytopenic| emphasizing the important

This member is a cytosolic protein

Found only where the chromosome cores are synapsed

Phosphorylated by ATR upon DNA damage

The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome

RSPO4 Rabbit Polyclonal Antibody, 50ul Centrifuges TPO-R deficient mice were severelyThis gene encodes a member of the R spondin family of proteins that share a common domain organization consisting of a signal peptide cysteine rich furin like domain thrombospondin domain and a C terminal basic region. The encoded protein may be involved in activation of Wnt beta catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.