Mouse Autophagy Related Protein 7, ATG7 ELISA Kit, 96T Reservoirs and exon 5 encodes the
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Mouse Autophagy Related Protein 7, ATG7 ELISA Kit, 96T Reservoirs and exon 5 encodes theE1 like activating enzyme involved in the 2 ubiquitin like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase 8 inhibition. Required for mitophagy which
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