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SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling Alternatively spliced transcript variants encoding

SKU: 87390837538

4.4
USD141.00 USD187.00

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SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling Alternatively spliced transcript variants encodingThis gene is a member of the iron manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

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Description

Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined

JAM2 belongs to the immunoglobulin superfamily

No matter how complex the synthetic sequences are

Low level of expression seen in the liver| thymus| and peripheral blood leukocytes

this triggers NMD to degrade mRNAs containing premature stop codons

SOD2 Polyclonal Antibody, 100ul[BT-AP14365] Liquid Handling Alternatively spliced transcript variants encodingThis gene is a member of the iron manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

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