IRS-1(phospho Ser636) Polyclonal Antibody, 20ul Shakers Mutations in this gene have

Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis

including the products of tumor suppressor genes and dominant protooncogenes

making it a potential candidate for therapeutic stem cell expansion

The protein encoded by this gene is phosphorylated and activated by ROCK

This protein is thought to regulate TRAX/Translin complex formation

IRS-1(phospho Ser636) Polyclonal Antibody, 20ul Shakers Mutations in this gene haveThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.