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c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis It is found in serum

SKU: 87582136063

4.9
PLN123.75 PLN148.75

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c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis It is found in serumThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a

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Description

It is found in serum and tissues and promotes cell adhesion and spreading

This gene autoregulates its expression by control of splicing of its first two introns

|PTM:The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8

Mutations in PNPT1 have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70

a transactivation domain enriched in acidic amino acids

c-Abl(Phospho-Tyr412) Rabbit Polyclonal Antibody, 100ul Protein Analysis It is found in serumThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a

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