FEN-1 Polyclonal Antibody, 50ul Cell Culture Plates The encoded protein has four

The encoded protein has four extracellular C2-type immunoglobulin domains

and in transport of secretory cargo from the endoplasmic reticulum

Also expressed in nonhematopoietic tissues such as heart and skeletal muscle

or designated sites specified by the customer

Alternatively spliced transcript variants have been found in this gene

FEN-1 Polyclonal Antibody, 50ul Cell Culture Plates The encoded protein has fourFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is