ERCC2 Polyclonal Antibody, 20ul PCR Series The encoded type 2 transmembrane

The encoded type 2 transmembrane protein may function as a cell surface antigen

The PDH complex contains three catalytic subunits| E1| E2| and E3| two regulatory subunits| E1 kinase and E1 phosphatase| and a non-catalytic subunit| E3 binding protein (E3BP)

The protein encoded by this gene contains seven ankyrin repeats

but not IL2

The encoded protein contains a B-box/coiled-coil motif

ERCC2 Polyclonal Antibody, 20ul PCR Series The encoded type 2 transmembraneThe nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2 TFIIH complex. The gene product has ATP dependent DNA helicase activity and belongs to the RAD3 XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer prone syndrome