ATP5G3 Polyclonal Antibody, 100ul In vitro Transcription A germline mutation of VHL

A germline mutation of VHL is the basis of familial inheritance of VHL syndrome

Mutation in this gene

and it functions as the high-affinity receptor for the coagulation factor VII

This gene is located on a region of chromosome 17q21

Defects in F7 can cause coagulopathy

ATP5G3 Polyclonal Antibody, 100ul In vitro Transcription A germline mutation of VHLATP5G3 (ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3) encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi subunit complexes: the soluble catalytic core, F1, and the membrane spanning component, Fo, comprising the proton channel.