Nesprin-3 Polyclonal Antibody, 50ul Pipette Holder Allelic variants of this gene

Allelic variants of this gene have been associated with autism and addiction vulnerability

|tissue specificity:Expressed in brain| skeletal muscle| spleen| thymus| prostate| testis| ovary| small intestine| and peripheral blood leukocytes

TP63 (tumor protein p63) encodes a member of the p53 family of transcription factors

The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation

It has a highly restricted target cell specificity acting only on endothelial cells

Nesprin-3 Polyclonal Antibody, 50ul Pipette Holder Allelic variants of this geneComponent of SUN protein containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.