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NM23-H1 Polyclonal Antibody, 50ul Shaker&Mixing and is itself also phosporylated

SKU: 88029602188

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PLN162.00 PLN182.00

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NM23-H1 Polyclonal Antibody, 50ul Shaker&Mixing and is itself also phosporylatedNME1 (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for NME1. Co transcription of NME1 and the neighboring downstream gene (NME2) generates

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Description

and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex

Isoform 1 but not isoform 2 is activated through autoproteolytic processing

The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells

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boasting high viscosity and robust cell attachment properties

NM23-H1 Polyclonal Antibody, 50ul Shaker&Mixing and is itself also phosporylatedNME1 (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for NME1. Co transcription of NME1 and the neighboring downstream gene (NME2) generates

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