HSP27 Polyclonal Antibody, 100ul[BT-AP04250] Purification NFKB1 encodes a 105 kD

NFKB1 encodes a 105 kD protein (nuclear factor kappa B subunit 1) which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein

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The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II

The precursor of the encoded protein (caspase 7) is cleaved by caspase 3 and 10

PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation

HSP27 Polyclonal Antibody, 100ul[BT-AP04250] Purification NFKB1 encodes a 105 kDHeat shock protein family B (small) member 1 encoded by HSPB1 is induced by environmental stress and developmental changes. Heat shock protein family B (small) member 1 is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in HSPB1 are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).