Presenilin 1(Phospho Ser357) Polyclonal Antibody, 50ul Plasmid Preparation All GTPases of the Ras

All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding

CNKSR2 encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras

PKC subfamily

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules

which results in the transcriptional activation of several immediate early genes

Presenilin 1(Phospho Ser357) Polyclonal Antibody, 50ul Plasmid Preparation All GTPases of the RasAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.