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ARBK1 Polyclonal Antibody, 50ul Primary Antibodies Multiple alternatively spliced transcript variants

SKU: 88389998259

4.4
PLN185.00 PLN214.00

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ARBK1 Polyclonal Antibody, 50ul Primary Antibodies Multiple alternatively spliced transcript variantsThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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Description

Multiple alternatively spliced transcript variants have been found for PDK1

thus is potentially associated with higher risk of breast cancer

to a lesser degree

NODAL (nodal growth differentiation factor) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

It is highly expressed during mitosis and elevated levels are found in many different types of cancer

ARBK1 Polyclonal Antibody, 50ul Primary Antibodies Multiple alternatively spliced transcript variantsThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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