NAB2 Polyclonal Antibody, 100ul Hepatocytes Mutations in ITCH are a

Mutations in ITCH are a cause of syndromic multisystem autoimmune disease

MDK has been targeted as a therapeutic for a variety of different disorders

and unlike most DEAD-box helicases

Class II molecules are heterodimers consisting of an alpha (DQA) and a beta chain (DQB)

Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain

NAB2 Polyclonal Antibody, 100ul Hepatocytes Mutations in ITCH are aNAB2 encodes a member of the family of NGFI A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo or hetero multimerize with other EGR or NAB proteins through a conserved N terminal domain, and repress transcription through two partially redundant C terminal domains. Transcriptional repression by the encoded protein is